Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524690 | 0.91 | CA1 (0.40) | TP53ALOX12LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8525770 | 0.82 | HCRTR2 (0.41) | CYP3A4ALDH1A1MEN1KMT2AHCRTR2 | |
| SCHEMBL8490872 | 0.81 | KDM4E (0.33) | TP53LMNAKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8492214 | 0.81 | KDM4E (0.37) | TP53LMNAKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8524135 | 0.79 | SMN1; SMN2 (0.39) | TP53KDM4ESMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL8487692 | 0.79 | KMT2A (0.39) | LMNAKDM4ESMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8488620 | 0.79 | NPC1 (0.35) | TP53LMNAKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8524545 | 0.77 | KMT2A (0.33) | TP53ALOX12LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7613973 | 0.77 | MLYCD (0.41) | LMNAKDM4ECYP2C9CYP2C19CYP1A2 | |
| SCHEMBL8892752 | 0.74 | ALDH1A1 (0.38) | LMNAKDM4ESMN1; SMN2HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |