Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | PPARA | Q07869 | 5/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524584 | 1.00 | FFAR1 (0.49) | FFAR1PPARGPPARAPPARDTP53 | |
| SCHEMBL6587033 | 0.91 | PPARG (0.51) | FFAR1PPARGPPARAPPARDTP53 | |
| SCHEMBL6587031 | 0.91 | PPARG (0.51) | FFAR1PPARGPPARAPPARDTP53 | |
| SCHEMBL6584029 | 0.87 | KDR (0.47) | FFAR1PPARGPPARAPPARDTP53 | |
| SCHEMBL6584026 | 0.87 | KDR (0.47) | FFAR1PPARGPPARAPPARDTP53 | |
| SCHEMBL8337476 | 0.86 | PPARG (0.49) | FFAR1PPARGPPARAPPARDTP53 | |
| SCHEMBL7160752 | 0.82 | KDR (0.65) | FFAR1PPARGPPARATP53KDR | |
| SCHEMBL7160754 | 0.82 | KDR (0.65) | FFAR1PPARGPPARATP53KDR | |
| SCHEMBL8337473 | 0.82 | FFAR1 (0.49) | FFAR1PPARGPPARAPPARDTP53 | |
| SCHEMBL6587331 | 0.82 | MAPT (0.49) | FFAR1PPARGPPARATP53KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932601-A | USEFUL FOR LOWERING BLOOD SUGAR AND LIPID IN BLOOD | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0783496-A1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996005186-A1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-22 | — | — | WO | disclosed |