Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524639 | 1.00 | HCRTR1 (0.45) | HCRTR1HCRTR2LMNAMGLLKMT2A | |
| SCHEMBL8526439 | 0.83 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL8526441 | 0.83 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL8524662 | 0.83 | ALDH1A1 (0.44) | HCRTR1LMNAMGLLMAPTSMN1; SMN2 | |
| SCHEMBL1822534 | 0.81 | LMNA (0.35) | HCRTR1HCRTR2LMNAKMT2AHSP90AA1 | |
| SCHEMBL1822223 | 0.81 | LMNA (0.35) | HCRTR1HCRTR2LMNAKMT2AHSP90AA1 | |
| SCHEMBL1822226 | 0.81 | LMNA (0.35) | HCRTR1HCRTR2LMNAKMT2AHSP90AA1 | |
| SCHEMBL8491859 | 0.80 | SMN1; SMN2 (0.40) | HCRTR1HCRTR2LMNAMGLLHSP90AA1 | |
| SCHEMBL1824608 | 0.78 | LMNA (0.33) | LMNAMGLLHSP90AA1MAPTHTT | |
| SCHEMBL2401819 | 0.78 | LMNA (0.33) | LMNAMGLLHSP90AA1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |