Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 15/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.43 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526441 | 1.00 | HCRTR1 (0.43) | HCRTR1HCRTR2CYP46A1TNKS | |
| SCHEMBL8524637 | 0.83 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL8524639 | 0.83 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL8490615 | 0.70 | HCRTR1 (0.44) | HCRTR1HCRTR2CYP46A1TNKS | |
| SCHEMBL8754832 | 0.70 | KDM4E (0.39) | — | |
| SCHEMBL17742692 | 0.69 | NPC1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL1827197 | 0.69 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL1824268 | 0.69 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL7820607 | 0.68 | HTR6 (0.47) | — | |
| SCHEMBL7820609 | 0.68 | HTR6 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |