Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669014 | 0.89 | EPHX2 (0.48) | LMNAALOX5HSD17B10ALDH1A1CES2 | |
| SCHEMBL27422843 | 0.84 | ALOX5 (0.44) | LTB4R2AGTR1CYP1A2NPC1RAB9A | |
| SCHEMBL27422841 | 0.84 | ALOX5 (0.44) | LTB4R2AGTR1CYP1A2NPC1RAB9A | |
| SCHEMBL9754294 | 0.81 | CYP1A2 (0.55) | CYP1A2HSD17B10ALDH1A1 | |
| SCHEMBL9847074 | 0.79 | TP53 (0.41) | CYP1A2NPC1RAB9AALDH1A1 | |
| SCHEMBL4242811 | 0.79 | AGTR1 (0.46) | LTB4R2AGTR1ALOX5CES2CES1 | |
| SCHEMBL8615970 | 0.78 | LPAR1 (0.54) | ALOX5 | |
| SCHEMBL18426131 | 0.77 | MMP2 (0.48) | ALOX5 | |
| SCHEMBL18426129 | 0.77 | MMP2 (0.48) | ALOX5 | |
| SCHEMBL18425887 | 0.77 | MMP2 (0.48) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749302-A4 | HYDROXAMIC ACID AND CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | SANOFI WINTHROP INC (US) | 1999-08-25 | — | — | EP | disclosed |
| EP-0749302-A1 | HYDROXAMIC ACID AND CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | SANOFI WINTHROP, INC. (US) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995022966-A1 | HYDROXAMIC ACID AND CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | SANOFI WINTHROP, INC. (US) | 1995-08-31 | — | — | WO | disclosed |