Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12115366 | 0.92 | EGFR (0.51) | EGFRSRCCCKBR | |
| SCHEMBL8524579 | 0.88 | EGFR (0.52) | EGFRHDAC6CCKBR | |
| SCHEMBL5635451 | 0.83 | HSD17B10 (0.43) | EGFRSRCCCKBR | |
| SCHEMBL6890519 | 0.81 | EGFR (0.50) | EGFRCCKBR | |
| SCHEMBL14610590 | 0.81 | CCKBR (0.39) | HDAC6CCKBR | |
| SCHEMBL19149276 | 0.81 | HTR2A (0.45) | CCKBR | |
| SCHEMBL31366241 | 0.81 | CCKBR (0.39) | HDAC6CCKBR | |
| SCHEMBL12397032 | 0.80 | MTNR1A (0.40) | CCKBR | |
| SCHEMBL7074697 | 0.78 | BCHE (0.48) | CCKBR | |
| SCHEMBL5539765 | 0.78 | CCKBR (0.39) | HDAC6CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999062900-A1 | OXINDOLE DERIVATIVES USED AS NEUROKININ RECEPTOR ANTAGONISTS | SANOFI-SYNTHELABO (FR) | 1999-12-09 | — | — | WO | disclosed |