Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 3/20 | 0.36 |
| ▸ | CDC25B | P30305 | 3/20 | 0.36 |
| ▸ | CDC25C | P30307 | 3/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.33 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524544 | 0.85 | CYP19A1 (0.44) | CDC25ACDC25BCDC25CDUSP3BACE1 | |
| SCHEMBL8525207 | 0.83 | KDM4E (0.42) | CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8524782 | 0.83 | CYP19A1 (0.48) | CDC25ACDC25BCDC25CDUSP3BACE1 | |
| SCHEMBL8525200 | 0.80 | BACE1 (0.35) | CDC25ACDC25BCDC25CDUSP3BACE1 | |
| SCHEMBL8524649 | 0.74 | RARA (0.44) | CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8524244 | 0.71 | CDK5 (0.38) | — | |
| SCHEMBL8524322 | 0.71 | CDC25A (0.49) | CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8524583 | 0.71 | CDC25A (0.44) | CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8524156 | 0.69 | CDC25A (0.45) | CDC25ACDC25BCDC25CDUSP3 | |
| SCHEMBL8524875 | 0.68 | KDM4E (0.41) | CDC25ACDC25BCDC25CDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |