Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 15/20 | 0.40 |
| ▸ | ITGAV | P06756 | 12/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584093 | 1.00 | BRD4 (0.48) | BRD4CREBBPITGB3ITGAVGAA | |
| SCHEMBL8503077 | 0.76 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL5196812 | 0.75 | BRD4 (0.57) | BRD4CREBBPITGB3ITGAVGAA | |
| SCHEMBL5191751 | 0.75 | BRD4 (0.57) | BRD4CREBBPITGB3ITGAVGAA | |
| SCHEMBL3455376 | 0.70 | ITGB3 (0.49) | BRD4CREBBPITGB3ITGAVITGA2B | |
| SCHEMBL8526495 | 0.70 | ITGB3 (0.49) | BRD4CREBBPITGB3ITGAVITGA2B | |
| SCHEMBL6663800 | 0.70 | MAPK1 (0.48) | BRD4CREBBPITGB3ITGAVGAA | |
| SCHEMBL6840060 | 0.67 | BRD4 (0.43) | BRD4ITGB3ITGAVITGA2B | |
| SCHEMBL677636 | 0.66 | BRD4 (1.00) | BRD4CREBBPMAPT | |
| SCHEMBL13711866 | 0.65 | BRD4 (0.47) | BRD4CREBBPITGB3ITGAVGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964928-A1 | ENZYMATIC RESOLUTION OF BENZODIAZEPINE-ACETIC ACID ESTERS WITH A LIPASE | SMITHKLINE BEECHAM PLC (GB) | 1999-12-22 | — | — | EP | claimed |
| WO-1998029561-A1 | ENZYMATIC RESOLUTION OF BENZODIAZEPINE-ACETIC ACID ESTERS WITH A LIPASE | SMITHKLINE BEECHAM PLC (GB) | 1998-07-09 | — | — | WO | claimed |
| EP-0964928-A1 | ENZYMATIC RESOLUTION OF BENZODIAZEPINE-ACETIC ACID ESTERS WITH A LIPASE | SMITHKLINE BEECHAM PLC (GB) | 1999-12-22 | — | — | EP | disclosed |
| WO-1998029561-A1 | ENZYMATIC RESOLUTION OF BENZODIAZEPINE-ACETIC ACID ESTERS WITH A LIPASE | SMITHKLINE BEECHAM PLC (GB) | 1998-07-09 | — | — | WO | disclosed |