Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 5/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | HRH2 | P25021 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525397 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2SLC6A2SLC6A4NPBWR1ALDH1A1 | |
| SCHEMBL8593864 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL8100298 | 0.72 | HTR5A (0.41) | SMN1; SMN2HTR1AADRB2ADRB1ADRA2A | |
| SCHEMBL5981298 | 0.68 | CYP1A2 (0.55) | HTR2AHTR2CMTNR1BMTNR1ACYP17A1 | |
| SCHEMBL6000211 | 0.68 | HTR1A (0.75) | HTR1AADRB2ADRB1ADRA2ADRD2 | |
| SCHEMBL9276510 | 0.68 | MTNR1B (0.48) | HTR1AADRB2ADRB1ADRA2ADRD2 | |
| SCHEMBL8590523 | 0.66 | KDM4E (0.47) | KDM4EALDH1A1CYP1A2MAPTHPGD | |
| SCHEMBL17948929 | 0.66 | MAPT (0.43) | SMN1; SMN2HTR2AMTNR1BMTNR1ANQO2 | |
| SCHEMBL8481561 | 0.66 | MYC (0.56) | SMN1; SMN2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL1402499 | 0.65 | MTNR1A (0.55) | HTR2AHTR2CMTNR1BMTNR1ANQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096895-A | Heterocyclic dihydrazole compounds and their use for controlling fungal plant diseases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0825992-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036633-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-11-21 | — | — | WO | disclosed |