Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15415011 | 0.98 | CA1 (0.42) | ITGB3ITGA2BCA1CA2CA7 | |
| SCHEMBL20001270 | 0.93 | CA1 (0.44) | ITGB3ITGA2BCA1CA2CA7 | |
| SCHEMBL28618599 | 0.87 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL6454726 | 0.87 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL10706331 | 0.87 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL28600066 | 0.87 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL30638293 | 0.87 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL3547988 | 0.86 | CA1 (0.46) | CA1CA2CA7CTSKMEN1 | |
| SCHEMBL150073 | 0.85 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL10431195 | 0.84 | CA1 (0.45) | ITGB3ITGA2BCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877278-A | SOLID PHASE SYNTHESIS USING TWO SUBMONOMERS-AN ACYLATING AGENT, E.G. A HALOACETIC ACID, AND A PRIMARY AMINE; CYCLIZATION TO PRODUCE MIMETICS OF DRUGS; ELIMINATION OF THE NECESSITY OF PROTECTION GROUPS | CHIRON CORPORATION (US) | 1999-03-02 | — | — | US | disclosed |
| US-5831005-A | ACYLATION, NUCLEOPHILIC DISPLACEMENT CYCLES | CHIRON CORPORATION (US) | 1998-11-03 | — | — | US | disclosed |