Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10706331 | 1.00 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL28618599 | 1.00 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL6454726 | 1.00 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL28600066 | 1.00 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL150073 | 0.98 | CTSK (0.51) | CTSKCTSS | |
| Hydrochloric Acid SCHEMBL2418363 | 0.97 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL3996361 | 0.93 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL8525452 | 0.87 | ITGB3 (0.42) | CTSKCTSS | |
| SCHEMBL3252315 | 0.86 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL15415011 | 0.85 | CA1 (0.42) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230406859-A1 | METHOTREXATE ANALOGS AND METHODS OF USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230406859-A1 | METHOTREXATE ANALOGS AND METHODS OF USE | MTX1, MTX2, MGMT | CTSK 3753/4885CTSS 4013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.