SCHEMBL10706331

SCHEMBL10706331

CCCCCCC(N)NC(=O)OC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSK P43235 15/20 0.50
CTSS P25774 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30638293 1.00 CTSK (0.50) CTSKCTSS
SCHEMBL28618599 1.00 CTSK (0.50) CTSKCTSS
SCHEMBL6454726 1.00 CTSK (0.50) CTSKCTSS
SCHEMBL28600066 1.00 CTSK (0.50) CTSKCTSS
SCHEMBL150073 0.98 CTSK (0.51) CTSKCTSS
Hydrochloric Acid SCHEMBL2418363 0.97 CTSK (0.50) CTSKCTSS
SCHEMBL3996361 0.93 CTSK (0.56) CTSKCTSS
SCHEMBL8525452 0.87 ITGB3 (0.42) CTSKCTSS
SCHEMBL3252315 0.86 CTSK (0.51) CTSKCTSS
SCHEMBL15415011 0.85 CA1 (0.42) CTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113105431-B Proteolysis targeting chimera and application thereof 河北康泰药业有限公司 2022-10-28 CN disclosed
EP-0135379-B1 BASIC HEXA- AND HEPTA-PEPTIDE VASOPRESSIN ANTAGONISTS SMITHKLINE BECKMAN CORPORATION (US) 1988-04-20 EP disclosed
US-4684621-A OLIGOPEPTIDES SMITHKLINE BECKMAN CORPORATION (US) 1987-08-04 US disclosed
US-4658015-A ANTAGONIST OF VASSOPRESSIN AND OXYTOCIN SMITHKLINE BECKMAN CORPORATION (US) 1987-04-14 US disclosed
US-4604378-A CYCLIC POLYPEPTIDES SMITHKLINE BECKMAN CORPORATION (US) 1986-08-05 US disclosed
EP-0182627-A2 Basic V1-vasopressin antagonists SMITHKLINE BECKMAN CORPORATION (US) 1986-05-28 EP disclosed
US-4543349-A Basic heptapeptide vasopressin antagonists SMITHKLINE BECKMAN CORPORATION (US) 1985-09-24 US disclosed
EP-0135379-A2 Basic hexa- and hepta-peptide vasopressin antagonists SMITHKLINE BECKMAN CORPORATION (US) 1985-03-27 EP disclosed