Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526016 | 0.83 | MAPK1 (0.38) | THRBMAPK1ALDH1A1TSHRHIF1A | |
| SCHEMBL8526037 | 0.82 | MAPK1 (0.44) | THRBMAPK1ALDH1A1TSHRHIF1A | |
| SCHEMBL8526431 | 0.80 | TSHR (0.46) | THRBMAPK1ALDH1A1TSHRTP53 | |
| SCHEMBL10437472 | 0.79 | THRB (0.56) | THRBMAPK1ALDH1A1TSHRTP53 | |
| SCHEMBL8883023 | 0.72 | MAPK1 (0.53) | THRBMAPK1ALDH1A1TSHRHIF1A | |
| SCHEMBL1724042 | 0.71 | THRB (0.49) | THRBMAPK1ALDH1A1TSHRTP53 | |
| SCHEMBL30510189 | 0.70 | THRB (0.52) | THRBMAPK1ALDH1A1TSHRTP53 | |
| SCHEMBL17320925 | 0.70 | THRB (0.59) | THRBMAPK1ALDH1A1TSHRTP53 | |
| SCHEMBL8525638 | 0.70 | HCAR2 (0.37) | THRBMAPK1ALDH1A1TSHRTP53 | |
| SCHEMBL13704977 | 0.70 | THRB (0.44) | THRBMAPK1ALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906937-A1 | Graft copolymer obtained by free-radical polymerisation with stable free-radicals, its preparation and uses | ELF ATOCHEM S.A. (FR) | 1999-04-07 | — | — | EP | disclosed |