Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 6/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.32 |
| ▸ | TTR | P02766 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772376 | 0.87 | MAPK1 (0.43) | HCAR2MAPK1AKR1B10AKR1B1MAOB | |
| SCHEMBL10435073 | 0.84 | MAPK1 (0.42) | HCAR2MAPK1AKR1B10AKR1B1MAOB | |
| SCHEMBL8526043 | 0.82 | MAPK1 (0.43) | MAPK1ALDH1A1ALOX15HSD17B10MEN1 | |
| SCHEMBL8526435 | 0.81 | ATM (0.33) | HCAR2 | |
| SCHEMBL9242885 | 0.80 | MAPK1 (0.43) | HCAR2MAPK1AKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL7692322 | 0.78 | HCAR2 (0.35) | HCAR2MAPK1AKR1B10AKR1B1MAOB | |
| SCHEMBL9862015 | 0.78 | HCAR2 (0.35) | HCAR2MAPK1AKR1B10AKR1B1MAOB | |
| SCHEMBL4224940 | 0.75 | CYP2D6 (0.38) | HCAR2MAPK1AKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL9862043 | 0.73 | MAPK1 (0.39) | MAPK1ALDH1A1ALOX15THRBMEN1 | |
| SCHEMBL10435435 | 0.73 | MAPK1 (0.34) | MAPK1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906937-A1 | Graft copolymer obtained by free-radical polymerisation with stable free-radicals, its preparation and uses | ELF ATOCHEM S.A. (FR) | 1999-04-07 | — | — | EP | disclosed |