Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 15/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 10/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524553 | 0.93 | HCRTR2 (0.40) | HCRTR2HCRTR1ENPP2GABRG2GABRB3 | |
| SCHEMBL8525146 | 0.93 | HCRTR2 (0.40) | HCRTR2HCRTR1ENPP2GABRG2GABRB3 | |
| SCHEMBL8490765 | 0.86 | L3MBTL1 (0.35) | HCRTR2HCRTR1GABRG2GABRB3GABRA5 | |
| SCHEMBL8524560 | 0.85 | HCRTR2 (0.42) | HCRTR2HCRTR1ENPP2GABRG2GABRB3 | |
| SCHEMBL8525154 | 0.85 | HCRTR2 (0.44) | HCRTR2HCRTR1ENPP2GABRG2GABRB3 | |
| SCHEMBL8524884 | 0.84 | LMNA (0.34) | HCRTR2GABRG2GABRB3GABRA5HSP90AA1 | |
| SCHEMBL8525770 | 0.84 | HCRTR2 (0.41) | HCRTR2HCRTR1ENPP2HSP90AA1ALDH1A1 | |
| SCHEMBL8391480 | 0.84 | ALDH1A1 (0.34) | HCRTR2HSP90AA1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8490014 | 0.84 | HTT (0.38) | HSP90AA1ALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL8492298 | 0.83 | L3MBTL1 (0.34) | HCRTR2GABRG2GABRB3GABRA5HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |