Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525737 | 1.00 | HPGD (0.44) | HPGDL3MBTL1HTR2AHTR2CHTR2B | |
| SCHEMBL6859836 | 0.73 | HTR2A (0.42) | HPGDL3MBTL1HTR2AHTR2CHTR2B | |
| SCHEMBL29447988 | 0.72 | SIGMAR1 (0.57) | HPGDL3MBTL1HTR2AHTR2CHTR2B | |
| SCHEMBL3054003 | 0.72 | SIGMAR1 (0.57) | HPGDL3MBTL1HTR2AHTR2CHTR2B | |
| SCHEMBL10387926 | 0.70 | HPGD (0.36) | HPGDL3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL10515088 | 0.70 | HPGD (0.36) | HPGDL3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL1119857 | 0.68 | HPGD (0.44) | HPGDL3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL4970172 | 0.68 | HPGD (0.44) | HPGDL3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8525588 | 0.68 | HPGD (0.44) | HPGDL3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| Methyl Alcohol SCHEMBL14815696 | 0.67 | KDM1A (0.46) | HTR2ASIGMAR1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |