SCHEMBL8525795

SCHEMBL8525795

Clc1ccccc1CC(Cl)(Cl)Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.52
PNMT P11086 1/20 0.52
TAAR1 Q96RJ0 4/20 0.48
PKM P14618 1/20 0.43
LMNA P02545 2/20 0.43
TSHR P16473 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
CHRM2 P08172 1/20 0.42
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
AOC3 Q16853 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KCNH2 Q12809 1/20 0.41
DPP4 P27487 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20583955 0.78 IDO1 (0.56) IDO1PNMTTAAR1PKMLMNA
SCHEMBL73408 0.78 IDO1 (0.50) IDO1PNMTTAAR1PKMLMNA
SCHEMBL6265284 0.78 IDO1 (0.50) IDO1PNMTTAAR1PKMLMNA
SCHEMBL9130054 0.78 IDO1 (0.45) IDO1PNMTTAAR1PKMLMNA
SCHEMBL14002893 0.78 IDO1 (0.45) IDO1PNMTTAAR1PKMLMNA
SCHEMBL10897137 0.78 ALDH1A1 (0.43) IDO1PNMTTAAR1LMNASLC6A2
SCHEMBL11848590 0.78 IDO1 (0.45) IDO1PNMTTAAR1PKMLMNA
SCHEMBL6708534 0.77 HSPA5 (0.40) IDO1PNMTTAAR1TSHRSLC6A2
SCHEMBL7717828 0.75 TSHR (0.39) IDO1PNMTTSHR
SCHEMBL9278409 0.75 IDO1 (0.46) IDO1PNMTTAAR1PKMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5245091-A PROCESS FOR THE PREPARATION OF 1,1-BIS(CHLOROPHENYL)-2,2,2-TRICHLOROETHANOL ELF ATOCHEM S.A. (FR) 1993-09-14 US claimed
CN-1612048-A Method for making printed circuit board FUJI PHOTO FILM CO LTD (JP) 2005-05-04 CN disclosed
CN-1130444-C Gasification reactor apparatus GRAVESSON ENERGY MAN LTD (GB) 2003-12-10 CN disclosed
CN-1272870-A Gasification reaction device GRAVESSON ENERGY MAN LTD (GB) 2000-11-08 CN disclosed
US-5877924-A Thin film magnetic head including negative photoresist NEC CORPORATION (JP) 1999-03-02 US disclosed
EP-0489140-B1 METHOD FOR PREPARING 1,1-BIS(CHLOROPHENYL) 2,2,2-TRICHLOROETHANOL ATOCHEM ELF SA (FR) 1995-08-02 EP disclosed
CN-1029120-C Process for preparing 1, 1-di (chlorophenyl) -2, 2, 2-trichloroethanol ATOCHEM (FR) 1995-06-28 CN disclosed
CN-1026689-C Process for dehydrochlorination of 1, 1-bis (R-phenyl) -2, 2, 2-trichloroethane ATOCHEM ELF SA (FR) 1994-11-23 CN disclosed
CN-1068101-A 1, two (the R-phenyl)-2,2 of 1-, the method for 2-trichloroethane dehydrochlorination FLF ATOCHEM S A (FR) 1993-01-20 CN disclosed
EP-0519807-A1 Process for the dehydrochlorination of 1,1-bis(R-phényl)-2,2,2-trichloroethanes ELF ATOCHEM S.A. (FR) 1992-12-23 EP disclosed
EP-0489140-A1 METHOD FOR PREPARING 1,1-BIS(CHLOROPHENYL) 2,2,2-TRICHLOROETHANOL. ATOCHEM ELF SA (FR) 1992-06-10 EP disclosed
WO-1992000264-A1 METHOD FOR PREPARING 1,1-BIS(CHLOROPHENYL) 2,2,2-TRICHLOROETHANOL ATOCHEM (FR) 1992-01-09 WO disclosed
CN-1057450-A 1, the method for making of 1-two (chloro-phenyl-)-trichloro-ethyl alcohol ATOCHEM (FR) 1992-01-01 CN disclosed
EP-0383054-A2 A process for preparing environmentally safe dicofol and its formulations AGAN CHEMICAL MANUFACTURERS LTD. (IL) 1990-08-22 EP disclosed
EP-0337815-A1 1-dimethylcarbamoyl-3-substituted-5-substituted-1H-1,2,4-triazoles SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-10-18 EP disclosed
EP-0098058-B1 SYNTHESIS OF PHENYLACETIC ACID ESTERS ELI LILLY AND COMPANY (US) 1986-02-19 EP disclosed
US-4426536-A Synthesis of phenylacetic acid esters ELI LILLY AND COMPANY (US) 1984-01-17 US disclosed
EP-0098058-A1 Synthesis of phenylacetic acid esters ELI LILLY AND COMPANY (US) 1984-01-11 EP disclosed