SCHEMBL6265284

SCHEMBL6265284

FC(F)(F)Cc1ccccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.50
PNMT P11086 1/20 0.50
TAAR1 Q96RJ0 3/20 0.46
PKM P14618 1/20 0.42
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CHRM2 P08172 1/20 0.41
KCNJ5 P48544 1/20 0.40
KCNJ3 P48549 1/20 0.40
GRIN2B Q13224 1/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
AOC3 Q16853 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9315343 0.82 PNMT (0.56) IDO1PNMTTAAR1TSHRCYP1A2
SCHEMBL9278409 0.82 IDO1 (0.46) IDO1PNMTTAAR1PKMLMNA
SCHEMBL11717665 0.82 IDO1 (0.38) IDO1PNMTTAAR1TSHR
Hydrochloric Acid SCHEMBL9276212 0.80 PNMT (0.50) IDO1PNMTTAAR1PKMLMNA
SCHEMBL8525795 0.78 IDO1 (0.52) IDO1PNMTTAAR1PKMLMNA
SCHEMBL11059677 0.77 TAAR1 (0.54) IDO1PNMTTAAR1PKMSLC6A2
SCHEMBL73408 0.76 IDO1 (0.50) IDO1PNMTTAAR1PKMLMNA
SCHEMBL20583955 0.76 IDO1 (0.56) IDO1PNMTTAAR1PKMLMNA
SCHEMBL4657492 0.74 IDO1 (0.36) IDO1PNMTTAAR1PKMLMNA
SCHEMBL17759866 0.74 TAAR1 (0.50) IDO1PNMTTAAR1PKMCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110061139-B Photovoltaic device comprising metal halide perovskite and passivating agent 牛津大学科技创新有限公司 2023-04-18 CN disclosed
CN-110078623-B Method for preparing 2,2 '-bis (trifluoromethyl) -4, 4' -dinitrobiphenyl 天津众泰材料科技有限公司 2022-05-06 CN disclosed
EP-1204632-B1 FUNGICIDAL COMPOUNDS HAVING A FLUOROVINYL- OR FLUOROPROPENYL-OXYPHENYLOXIME MOIETY AND PROCESS FOR THE PREPARATION THEREOF KOREA RES INST CHEM TECH (KR) 2005-11-09 EP disclosed
EP-1144406-B1 ANTIFUNGAL AZOLE DERIVATIVES HAVING A FLUORINATED VINYL GROUP AND PROCESS FOR PREPARING SAME KOREA RES INST CHEM TECH (KR) 2003-07-30 EP disclosed
US-6552080-B1 High fungicidal activity against a wide spectrum of plant pathogenic fungi KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2003-04-22 US disclosed
EP-1204632-A4 FUNGICIDAL COMPOUNDS HAVING A FLUOROVINYL- OR FLUOROPROPENYL-OXYPHENYLOXIME MOIETY AND PROCESS FOR THE PREPARATION THEREOF KOREA RES INST CHEM TECH (KR) 2003-03-26 EP disclosed
EP-1144406-A4 ANTIFUNGAL AZOLE DERIVATIVES HAVING A FLUORINATED VINYL GROUP AND PROCESS FOR PREPARING SAME KOREA RES INST CHEM TECH (KR) 2002-07-24 EP disclosed
EP-1204632-A1 FUNGICIDAL COMPOUNDS HAVING A FLUOROVINYL- OR FLUOROPROPENYL-OXYPHENYLOXIME MOIETY AND PROCESS FOR THE PREPARATION THEREOF Korea Research Institute of Chemical Technology (KR) 2002-05-15 EP disclosed
EP-1144406-A1 ANTIFUNGAL AZOLE DERIVATIVES HAVING A FLUORINATED VINYL GROUP AND PROCESS FOR PREPARING SAME Korea Research Institute of Chemical Technology (KR) 2001-10-17 EP disclosed
WO-2001012585-A1 FUNGICIDAL COMPOUNDS HAVING A FLUOROVINYL- OR FLUOROPROPENYL-OXYPHENYLOXIME MOIETY AND PROCESS FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2001-02-22 WO disclosed
WO-2000043390-A1 ANTIFUNGAL AZOLE DERIVATIVES HAVING A FLUORINATED VINYL GROUP AND PROCESS FOR PREPARING SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2000-07-27 WO disclosed
US-6034086-A VIRICIDES; AIDS THERAPY UBE INDUSTRIES, LTD. 2000-03-07 US disclosed
EP-0206951-B1 PROCESS FOR THE PERFLUOROALKYLATION OF AROMATIC DERIVATIVES RHONE-POULENC CHIMIE (FR) 1990-03-21 EP disclosed
EP-0206951-A2 Process for the perfluoroalkylation of aromatic derivatives RHONE-POULENC CHIMIE (FR) 1986-12-30 EP disclosed