Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265284 | 0.82 | IDO1 (0.50) | IDO1PNMTPKMTAAR1NPC1 | |
| SCHEMBL14002893 | 0.77 | IDO1 (0.45) | IDO1PNMTPKMTAAR1NPC1 | |
| Hydrochloric Acid SCHEMBL9276212 | 0.77 | PNMT (0.50) | IDO1PNMTPKMTAAR1GRIN2B | |
| SCHEMBL8525795 | 0.75 | IDO1 (0.52) | IDO1PNMTPKMTAAR1NPC1 | |
| SCHEMBL73408 | 0.73 | IDO1 (0.50) | IDO1PNMTPKMTAAR1NPC1 | |
| SCHEMBL20583955 | 0.73 | IDO1 (0.56) | IDO1PNMTPKMTAAR1NPC1 | |
| Hydrochloric Acid SCHEMBL27858949 | 0.72 | PKM (0.43) | IDO1PNMTPKMTAAR1NPC1 | |
| SCHEMBL28002664 | 0.72 | IDO1 (0.41) | IDO1PNMTPKMTAAR1NPC1 | |
| SCHEMBL31500766 | 0.70 | SMN1; SMN2 (0.40) | IDO1PNMTNR3C1NR3C2KCNJ5 | |
| SCHEMBL20988713 | 0.70 | RAB9A (0.40) | IDO1PNMTPKMTAAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074784-A2 | NOVEL FLUORINATED SULFAMIDES EXHIBITING NEUROPROTECTIVE ACTION AND THEIR METHOD OF USE | ADVANCED NEURAL DYNAMICS, INC. (US) | 2012-06-07 | — | — | WO | disclosed |