Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3828293 | 0.85 | POLB (0.38) | HRH3POLBL3MBTL1CHRNB2CHRNA5 | |
| SCHEMBL6318180 | 0.83 | KMT2A (0.43) | KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL13929716 | 0.82 | CHRNB2 (0.48) | KMT2AHRH3CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL2566481 | 0.82 | HSD17B10 (0.38) | KMT2AALDH1A1POLBL3MBTL1 | |
| SCHEMBL3832136 | 0.82 | HSD17B10 (0.38) | KMT2AALDH1A1POLBL3MBTL1 | |
| SCHEMBL7059997 | 0.82 | POLB (0.42) | HRH3POLBL3MBTL1CHRNB2CHRNA5 | |
| SCHEMBL7298229 | 0.82 | POLB (0.42) | HRH3POLBL3MBTL1CHRNB2CHRNA5 | |
| SCHEMBL14376641 | 0.81 | L3MBTL1 (0.45) | KMT2AHRH3ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL2041988 | 0.79 | ALDH1A1 (0.40) | KMT2AHRH3ALDH1A1GABRA1GABRG2 | |
| SCHEMBL19947209 | 0.79 | ALDH1A1 (0.40) | KMT2AHRH3ALDH1A1GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923539-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998003473-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-01-29 | — | — | WO | disclosed |