Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431368 | 0.87 | NOTUM (0.34) | NISCH | |
| SCHEMBL9804988 | 0.85 | AHR (0.50) | KMOMEN1ALDH1A1MAPTHTT | |
| SCHEMBL16456691 | 0.84 | ERCC1 (0.41) | NISCHRPA1PTGS2PTGS1ERCC1 | |
| SCHEMBL7470031 | 0.82 | ADORA2A (0.43) | RPA1PTGS2PTGS1ERCC1ERCC4 | |
| SCHEMBL1116582 | 0.81 | GABRP (0.38) | PTGS2MEN1ALDH1A1KMT2A | |
| SCHEMBL4561791 | 0.80 | GRM2 (0.40) | NISCHRPA1PTGS2HPGD | |
| SCHEMBL4831885 | 0.80 | PTGS2 (0.42) | NISCHRPA1PTGS2PTGS1ERCC1 | |
| SCHEMBL436851 | 0.78 | AHR (0.38) | ALDH1A1MAPT | |
| SCHEMBL2013527 | 0.77 | GABRP (0.30) | — | |
| SCHEMBL2012652 | 0.76 | GABRP (0.43) | NISCHMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985919-A | INSECTICIDES AND FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-16 | — | — | US | disclosed |