Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | F9 | P00740 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490965 | 0.85 | F9 (0.42) | SMYD3S1PR1SMN1; SMN2HSP90AA1MAPT | |
| SCHEMBL8524846 | 0.80 | CTSS (0.40) | SMYD3SMN1; SMN2HSP90AA1MAPTHTT | |
| SCHEMBL8167425 | 0.79 | SMN1; SMN2 (0.42) | PCSK9SMN1; SMN2HSP90AA1MAPTHTT | |
| SCHEMBL8176394 | 0.78 | CYP1A2 (0.46) | PCSK9SMN1; SMN2HSP90AA1MAPTHTT | |
| SCHEMBL8491847 | 0.76 | SMN1; SMN2 (0.36) | PCSK9SMYD3S1PR1SMN1; SMN2HSP90AA1 | |
| SCHEMBL8491854 | 0.76 | SMN1; SMN2 (0.36) | PCSK9SMYD3S1PR1SMN1; SMN2HSP90AA1 | |
| SCHEMBL8176120 | 0.75 | KDM4E (0.36) | PCSK9SMYD3SMN1; SMN2HSP90AA1MAPT | |
| SCHEMBL1825556 | 0.74 | MAPT (0.33) | SMYD3MAPTHTTGPR119SYK | |
| SCHEMBL1822912 | 0.74 | KDM4E (0.36) | SMYD3SMN1; SMN2HSP90AA1MAPTHTT | |
| SCHEMBL6748543 | 0.74 | ERCC5 (0.39) | SMN1; SMN2MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |