Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490965 | 0.83 | F9 (0.42) | GPR119SMYD3TTKHSP90AA1MAPT | |
| SCHEMBL8189685 | 0.80 | ALDH1A1 (0.47) | GPR119MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8525971 | 0.80 | PCSK9 (0.38) | GPR119SMYD3HSP90AA1MAPTHTT | |
| SCHEMBL8180740 | 0.80 | MAPK10 (0.43) | CTSSMAPK10LRRK2NOTUMHSP90AA1 | |
| SCHEMBL1826021 | 0.78 | SMN1; SMN2 (0.36) | GPR119SMYD3MAPTHTTSMN1; SMN2 | |
| SCHEMBL8175262 | 0.77 | CYP1A2 (0.48) | CTSSGPR119MAPK10LRRK2NOTUM | |
| SCHEMBL8524403 | 0.76 | CTSS (0.41) | CTSSGPR119MAPK10LRRK2NOTUM | |
| SCHEMBL8524448 | 0.75 | GPR119 (0.37) | CTSSGPR119MAPK10LRRK2NOTUM | |
| SCHEMBL8524446 | 0.75 | GPR119 (0.37) | CTSSGPR119MAPK10LRRK2NOTUM | |
| SCHEMBL8191987 | 0.75 | L3MBTL1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |