Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247673 | 0.77 | PDE4A (0.61) | GAAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31090146 | 0.72 | GAA (0.77) | GAALMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL7254762 | 0.72 | ALDH1A1 (0.76) | GAALMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL10208072 | 0.71 | ALDH1A1 (0.55) | GAALMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL24603063 | 0.71 | GAA (0.59) | GAAALDH1A1AOC3CYP1A2CYP3A4 | |
| SCHEMBL7398838 | 0.71 | GAA (0.59) | GAALMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL3716351 | 0.70 | GAA (0.62) | GAAALDH1A1AOC3CYP1A2CYP3A4 | |
| SCHEMBL687841 | 0.70 | GAA (0.67) | GAALMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL3949236 | 0.70 | GAA (0.57) | GAALMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL13181092 | 0.68 | GAA (0.69) | GAALMNAALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414730-B1 | Chemical Compounds and pharmaceutical compositions capable of releasing a drug | MILLS RANDELL L (US) | 1999-12-15 | — | — | EP | disclosed |