SCHEMBL8526006

SCHEMBL8526006

O=C(c1ccccc1)C(O)C1=CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
LMNA P02545 1/20 0.52
CES1 P23141 1/20 0.52
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 4/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 2/20 0.39
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TSHR P16473 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
MDM2 Q00987 1/20 0.37
TBXAS1 P24557 1/20 0.37
MCL1 Q07820 1/20 0.37
MITF O75030 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29216098 0.80 TDP1 (0.39) CES2LMNACES1TDP1L3MBTL1
SCHEMBL10171591 0.80 HDAC4 (0.38) LMNAL3MBTL1ALDH1A1KMT2AMAPT
SCHEMBL26820449 0.78 TSHR (0.45) LMNACES1TDP1L3MBTL1ALDH1A1
SCHEMBL8469882 0.75 NPSR1 (0.36) TDP1L3MBTL1ALDH1A1KMT2AMAPT
SCHEMBL29216002 0.74 TDP1 (0.40) CES2LMNACES1TDP1L3MBTL1
SCHEMBL28065461 0.74 HDAC4 (0.34) NPSR1HPGD
SCHEMBL10362582 0.72 NPSR1 (0.50) LMNATDP1L3MBTL1KMT2AHTT
SCHEMBL8526007 0.71 LMNA (0.50) CES2LMNACES1TDP1L3MBTL1
Benzoin SCHEMBL29201872 0.71 CES2 (0.84) CES2LMNACES1TDP1L3MBTL1
SCHEMBL10886779 0.70 KDM4E (0.39) ALDH1A1KMT2AMAPTHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11013714-B2 Use of homoeriodictyol (HED) for reducing the gastric acid secretion-stimulating effect of n-acetyl-4-aminophenol (Paracetamol) SYMRISE AG (DE) 2021-05-25 US claimed
US-20190091199-A1 THE USE OF HOMOERIODICTYOL (HED) FOR REDUCING THE GASTRIC ACID SECRETION-STIMULATING EFFECT OF N-ACETYL-4-AMINOPHENOL (PARACETAMOL) SYMRISE AG (DE) 2019-03-28 US claimed
US-9556363-B2 Copper barrier chemical-mechanical polishing composition CABOT MICROELECTRONICS CORPORATION (US) 2017-01-31 US disclosed
US-20150376463-A1 COPPER BARRIER CHEMICAL-MECHANICAL POLISHING COMPOSITION CMC MATERIALS LLC 2015-12-31 US disclosed
WO-1999059988-A1 NEW PROCESS ASTRAZENECA AB (SE) 1999-11-25 WO disclosed
US-5336600-A Incubating samples with fluorescent reagent which has observable decrease in emitted light in presence of microorganisms, kits for screening blood, urine, foods, water drugs or cosmetics BIO MERIEUX (FR) 1994-08-09 US disclosed