Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | VDR | P11473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29402885 | 0.82 | EGFR (0.42) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL9643682 | 0.77 | MAPT (0.54) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL10895225 | 0.76 | MAPT (0.52) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL21870870 | 0.76 | MAPT (0.47) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL20556024 | 0.76 | MAPT (0.47) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL9541704 | 0.76 | VDR (0.53) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL6102218 | 0.75 | MAPT (0.49) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL30513824 | 0.75 | MAPT (0.44) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL21397382 | 0.74 | VDR (0.55) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL21870867 | 0.74 | MAPT (0.45) | MAPTALDH1A1KDM4EGAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652212-B1 | Substituted fluorine-containing beta-indolebutyric acid derivatives, their preparation and their use as plant growth regulators | AGENCY IND SCIENCE TECHN (JP) | 1998-03-11 | — | — | EP | claimed |
| CN-113943244-B | Sulfur-containing gamma, gamma-diindolylbutyramide compounds prepared by difunctional reactions | 温州大学 | 2023-05-23 | — | — | CN | disclosed |