Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 5/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21397382 | 0.84 | VDR (0.55) | VDRKDM1AAHRMAPTALDH1A1 | |
| SCHEMBL10895225 | 0.82 | MAPT (0.52) | VDRKDM1AAHRMAPTALDH1A1 | |
| SCHEMBL8591132 | 0.80 | KDM1A (0.69) | VDRKDM1AAHRMAPTALDH1A1 | |
| SCHEMBL31567580 | 0.79 | VDR (0.62) | VDRKDM1AAHRMAPTALDH1A1 | |
| SCHEMBL8997990 | 0.79 | VDR (0.67) | VDRKDM1AAHRMAPTALDH1A1 | |
| SCHEMBL19055128 | 0.77 | VDR (0.53) | VDRKDM1AAHRMAPTALDH1A1 | |
| SCHEMBL9543434 | 0.76 | KIF11 (0.39) | MAPTALDH1A1KDM4EGAATDP1 | |
| SCHEMBL8526126 | 0.76 | MAPT (0.47) | VDRKDM1AAHRMAPTALDH1A1 | |
| SCHEMBL11691667 | 0.76 | VDR (0.58) | VDRKDM1AAHRMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9540790 | 0.75 | KIF11 (0.38) | MAPTALDH1A1KDM4EGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010119-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-27 | — | — | WO | disclosed |