Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | VDR | P11473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20556016 | 1.00 | MAPT (0.45) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL27257001 | 0.93 | MAPT (0.43) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL21870870 | 0.90 | MAPT (0.47) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL20556024 | 0.90 | MAPT (0.47) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL20555800 | 0.80 | VDR (0.51) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL31000598 | 0.80 | VDR (0.51) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL18135258 | 0.80 | VDR (0.51) | MAPTALDH1A1KDM4EGAACASP1 | |
| SCHEMBL20551986 | 0.75 | GPR84 (0.61) | MAPTKDM4EGAASMN1; SMN2KMT2A | |
| SCHEMBL31000506 | 0.75 | GPR84 (0.61) | MAPTKDM4EGAASMN1; SMN2KMT2A | |
| SCHEMBL21870762 | 0.75 | GPR84 (0.61) | MAPTKDM4EGAASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2024-07-02 | — | — | US | disclosed |
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2024-07-02 | — | — | US | disclosed |
| US-20200340024-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-10-29 | — | — | US | disclosed |
| US-10612056-B2 | Beta-substituted non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | AANAT, AADAT, TPH1 | MAPT 2576/4885ALDH1A1 944/4885KDM4E 2762/4885 |
| US-20200340024-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | AANAT, AADAT, TPH1 | MAPT 2576/4885ALDH1A1 944/4885KDM4E 2762/4885 |
| US-10612056-B2 | Beta-substituted non-canonical amino acids | AANAT, TPH1, AADAT | MAPT 2234/4885ALDH1A1 1216/4885KDM4E 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.