Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 8/20 | 0.40 |
| ▸ | MC3R | P41968 | 6/20 | 0.40 |
| ▸ | MC1R | Q01726 | 6/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 6/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525723 | 0.88 | TGM2 (0.39) | MC4RMC3RMC1RTPSAB1MC5R | |
| SCHEMBL8526191 | 0.88 | F7 (0.42) | MC4RMC3RMC1RTPSAB1ACHE | |
| Trifluoroacetic Acid SCHEMBL8528536 | 0.85 | NPY4R (0.36) | MC4RMC3RMC1RMC5RF7 | |
| SCHEMBL8612160 | 0.81 | TGM2 (0.37) | MC4RMC3RMC1RTPSAB1MC5R | |
| SCHEMBL7059809 | 0.80 | NPY1R (0.42) | TPSAB1 | |
| SCHEMBL6899868 | 0.80 | NPY1R (0.42) | TPSAB1 | |
| SCHEMBL8528194 | 0.79 | F7 (0.40) | MC4RMC3RMC1RTPSAB1MC5R | |
| SCHEMBL7750702 | 0.79 | F7 (0.43) | ACHEHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8525945 | 0.78 | F7 (0.42) | MC4RMC3RMC1RACHEHDAC3 | |
| SCHEMBL7045274 | 0.77 | KDM4E (0.42) | MC4RMC3RMC1RMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |