Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6463695 | 0.71 | SIGMAR1 (0.31) | SIGMAR1 | |
| Ethylene Glycol SCHEMBL27633980 | 0.65 | SIGMAR1 (0.33) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7615269 | 0.64 | BRD4 (0.35) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8525226 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL8525556 | 0.64 | RET (0.32) | — | |
| Hydrochloric Acid SCHEMBL4457339 | 0.63 | BRD4 (0.37) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6053912 | 0.62 | BRD4 (0.36) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8526645 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL1065901 | 0.59 | BRD4 (0.34) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3627506 | 0.59 | HTR2A (0.37) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953580-A1 | Preparation and use of heterogeneous catalyst components for olefins polymerization | REPSOL QUIMICA S.A. (ES) | 1999-11-03 | — | — | EP | disclosed |