Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4457339 | 0.79 | BRD4 (0.37) | BRD4CCL2HTR2AHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6053912 | 0.77 | BRD4 (0.36) | BRD4CCL2HTR2AHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7615269 | 0.76 | BRD4 (0.35) | BRD4CCL2HTR2AHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3627506 | 0.74 | HTR2A (0.37) | BRD4CCL2HTR2AHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8534598 | 0.69 | GPR3 (0.32) | BRD4CCL2HTR2AHTR6CYP2D6 | |
| Hydrochloric Acid SCHEMBL7641256 | 0.69 | HTR2A (0.33) | BRD4CCL2HTR2AHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7642388 | 0.69 | SIGMAR1 (0.32) | BRD4CCL2HTR2AHTR6SIGMAR1 | |
| SCHEMBL3404077 | 0.68 | HTR2A (0.38) | BRD4CCL2HTR2AHTR6SIGMAR1 | |
| SCHEMBL4652559 | 0.68 | HTR2A (0.38) | BRD4CCL2HTR2AHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1131735 | 0.68 | HTR2A (0.34) | BRD4CCL2HTR2AHTR6SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048950-A | Polymer having long isotactic sequences and randomly-distributed ethylene content obtained by polymerizing propylene in presence of specific catalysts | TARGOR GMBH (DE) | 2000-04-11 | — | — | US | claimed |
| US-5700896-A | Polymer having long isotactic sequences and randomly-distributed ethylene content obtained by polymerizing propylene in presence of specific catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-23 | — | — | US | claimed |
| EP-0355447-B1 | PROPYLENE ISOBLOCK POLYMER AND PROCESS FOR PREPARING THE SAME | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-16 | — | — | EP | claimed |
| EP-3436521-B1 | LOW CRYSTALLINE POLYMER COMPOSITIONS PREPARED IN A DUAL REACTOR | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2022-02-16 | — | — | EP | disclosed |
| US-10926517-B2 | Multilayer films and methods of making the same | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-02-23 | — | — | US | disclosed |
| US-10894393-B2 | Multilayer films and methods of making the same | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-01-19 | — | — | US | disclosed |
| EP-3390056-B1 | LOW CRYSTALLINE POLYMER COMPOSITIONS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3436521-A1 | LOW CRYSTALLINE POLYMER COMPOSITIONS PREPARED IN A DUAL REACTOR | ExxonMobil Chemical Patents Inc. (US) | 2019-02-06 | — | — | EP | disclosed |
| EP-3390056-A1 | LOW CRYSTALLINE POLYMER COMPOSITIONS | ExxonMobil Chemical Patents Inc. (US) | 2018-10-24 | — | — | EP | disclosed |
| EP-1896542-B1 | PLASTICIZED FUNCTIONALIZED PROPYLENE COPOLYMER ADHESIVE COMPOSITION | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2018-06-20 | — | — | EP | disclosed |
| US-20180126707-A1 | Multilayer Films and Methods of Making the Same | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-05-10 | — | — | US | disclosed |
| US-20040192823-A1 | Elastic blends of semicrystalline propylene polymers and high glass transition temperature materials | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-09-30 | — | — | US | disclosed |
| WO-2004063270-A2 | ELASTIC ARTICLES AND PROCESSES FOR THEIR MANUFACTURE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-07-29 | — | — | WO | disclosed |
| US-6562886-B1 | A propylene homopolymer or a copolymer of propylene and an alpha -olefin with at least 4 carbon atoms, which is produced through polymerization in the presence of a metallocene catalyst and which has an increased isotactic pentad fraction | IDEMISTSU PETROCHEMICAL CO., LTD. (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-0686649-B1 | PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM | IDEMITSU KOSAN CO (JP) | 2000-08-02 | — | — | EP | disclosed |
| EP-1006149-A1 | PROPYLENE POLYMER COMPOSITION AND FILMS MADE THEREFROM | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2000-06-07 | — | — | EP | disclosed |
| US-6048950-A | Polymer having long isotactic sequences and randomly-distributed ethylene content obtained by polymerizing propylene in presence of specific catalysts | TARGOR GMBH (DE) | 2000-04-11 | — | — | US | disclosed |
| US-5700896-A | Polymer having long isotactic sequences and randomly-distributed ethylene content obtained by polymerizing propylene in presence of specific catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-23 | — | — | US | disclosed |
| US-5670580-A | POLYMERS FOR ANTISTATIC AGENTS, ADHESIVES AND FIREPROOFING | IDEMITSU KOSAN CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0686649-A1 | PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1995-12-13 | — | — | EP | disclosed |