Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.55 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.52 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | STAT6 | P42226 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10895066 | 0.99 | RAD52 (0.57) | RAD52UHRF1MCHR1PTK2SMARCA2 | |
| Hydrochloric Acid SCHEMBL10897440 | 0.92 | MCHR1 (0.53) | RAD52UHRF1MCHR1ALDH1A1HSD17B10 | |
| SCHEMBL3362006 | 0.80 | ALDH1A1 (0.62) | RAD52UHRF1MCHR1SMARCA2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9229456 | 0.76 | SIGMAR1 (0.52) | DRD2DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9223939 | 0.76 | SIGMAR1 (0.52) | DRD2DRD3SIGMAR1 | |
| SCHEMBL3741758 | 0.75 | KDM4E (0.60) | ALDH1A1HSD17B10CYP1A2CYP2C9KMT2A | |
| SCHEMBL24162935 | 0.75 | CYP1A2 (0.52) | RAD52UHRF1MCHR1SMARCA2ALDH1A1 | |
| SCHEMBL20125128 | 0.75 | HTT (0.68) | RAD52UHRF1MCHR1PTK2SMARCA2 | |
| SCHEMBL8526913 | 0.75 | DRD3 (0.58) | CYP1A2DRD2DRD3SIGMAR1 | |
| SCHEMBL22022169 | 0.74 | RAD52 (0.52) | RAD52UHRF1MCHR1PTK2SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539281-B1 | Naphthamides, process for their preparation and their application in the therapeutical field | INST NAT SANTE RECH MED (FR) | 1998-12-30 | — | — | EP | disclosed |