Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | FABP3 | P05413 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL8526004 | 1.00 | GPR84 (0.41) | GPR84PPARGPPARDPPARAFABP3 | |
| Stearic Acid SCHEMBL28219681 | 0.93 | FABP3 (0.44) | FABP3 | |
| Palmitic Acid SCHEMBL28297877 | 0.93 | GPR84 (0.47) | GPR84PPARGPPARDPPARAFABP3 | |
| Stearic Acid SCHEMBL17498239 | 0.93 | GPR84 (0.47) | GPR84PPARGPPARDPPARAFABP3 | |
| SCHEMBL28067367 | 0.85 | FFAR4 (0.56) | GPR84ALDH1A1TDP1FFAR1FFAR4 | |
| Stearic Acid SCHEMBL27343083 | 0.79 | FNTA (0.36) | GPR84PPARGPPARDPPARAFABP3 | |
| Propionic Acid SCHEMBL28130435 | 0.77 | LMNA (0.39) | TSHRALDH1A1KMT2A | |
| SCHEMBL11857121 | 0.76 | LMNA (0.34) | ALDH1A1MEN1KMT2AHSD17B10 | |
| Dibutyl Sebacate SCHEMBL28018814 | 0.76 | DGKA (0.45) | TSHRALDH1A1KMT2A | |
| SCHEMBL787107 | 0.75 | TSHR (0.48) | TSHRALDH1A1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972383-A | Solid orally administerable raloxifene hydrochloride pharmaceutical formulation | ELI LILLY AND COMPANY (US) | 1999-10-26 | — | — | US | disclosed |