Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9092510 | 0.99 | DRD3 (0.51) | DRD3KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8528941 | 0.85 | DRD3 (0.46) | DRD3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL9091554 | 0.84 | DRD3 (0.45) | DRD3DRD2DRD4 | |
| SCHEMBL8529533 | 0.81 | DRD2 (0.40) | DRD3ALDH1A1CYP1A2CYP3A4DRD2 | |
| SCHEMBL8526372 | 0.81 | KDM4E (0.57) | DRD3KDM4EALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9091515 | 0.80 | DRD2 (0.39) | DRD3ALDH1A1CYP1A2CYP3A4DRD2 | |
| Hydrochloric Acid SCHEMBL8526377 | 0.80 | KDM4E (0.56) | DRD3KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8529262 | 0.73 | SIGMAR1 (0.48) | DRD3DRD2DRD4 | |
| SCHEMBL9090897 | 0.73 | KDM4E (0.55) | DRD3KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7392064 | 0.72 | DRD3 (0.62) | DRD3KDM4EALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539281-B1 | Naphthamides, process for their preparation and their application in the therapeutical field | INST NAT SANTE RECH MED (FR) | 1998-12-30 | — | — | EP | claimed |