Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9091554 | 0.99 | DRD3 (0.45) | DRD3DRD2DRD4SIGMAR1 | |
| SCHEMBL8529262 | 0.89 | SIGMAR1 (0.48) | DRD3DRD2DRD4SIGMAR1 | |
| SCHEMBL8526371 | 0.85 | DRD3 (0.52) | DRD3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL9092510 | 0.84 | DRD3 (0.51) | DRD3DRD2DRD4 | |
| SCHEMBL8529533 | 0.84 | DRD2 (0.40) | DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL9091515 | 0.83 | DRD2 (0.39) | DRD3DRD2 | |
| SCHEMBL8527038 | 0.80 | DRD3 (0.55) | DRD3DRD2DRD4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8528848 | 0.79 | DRD3 (0.54) | DRD3DRD2DRD4SIGMAR1 | |
| SCHEMBL8526913 | 0.73 | DRD3 (0.58) | DRD3DRD2DRD4SIGMAR1 | |
| SCHEMBL8527632 | 0.72 | HTT (0.42) | DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539281-B1 | Naphthamides, process for their preparation and their application in the therapeutical field | INST NAT SANTE RECH MED (FR) | 1998-12-30 | — | — | EP | claimed |