Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 10/20 | 0.63 |
| ▸ | CTSL | P07711 | 3/20 | 0.63 |
| ▸ | CTSS | P25774 | 3/20 | 0.63 |
| ▸ | MME | P08473 | 7/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.55 |
| ▸ | ACE | P12821 | 4/20 | 0.53 |
| ▸ | CPA1 | P15085 | 4/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111430 | 1.00 | CTSB (0.63) | CTSBCTSLCTSSMMEACE2 | |
| SCHEMBL7040960 | 0.86 | CTSB (0.61) | CTSBCTSLCTSSMME | |
| SCHEMBL7040956 | 0.86 | CTSB (0.61) | CTSBCTSLCTSSMME | |
| SCHEMBL8586104 | 0.86 | CTSB (0.61) | CTSBCTSLCTSSMME | |
| SCHEMBL9194663 | 0.86 | CTSL (0.68) | CTSBCTSLCTSSMMEACE2 | |
| SCHEMBL8120784 | 0.86 | CTSL (0.68) | CTSBCTSLCTSSMMEACE2 | |
| SCHEMBL8120788 | 0.86 | CTSL (0.68) | CTSBCTSLCTSSMMEACE2 | |
| SCHEMBL8120139 | 0.84 | CTSB (0.63) | CTSBCTSLCTSS | |
| SCHEMBL8355579 | 0.84 | CTSB (0.56) | CTSBCTSLCTSSMMEACE2 | |
| SCHEMBL8355762 | 0.83 | MME (0.65) | CTSBCTSLCTSSMMEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |