Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 14/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
| ▸ | USP14 | P54578 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824268 | 1.00 | HCRTR1 (0.33) | HCRTR1HCRTR2KDM6BMAP3K5USP14 | |
| SCHEMBL1822534 | 0.81 | LMNA (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL1822226 | 0.81 | LMNA (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL1822223 | 0.81 | LMNA (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL5163749 | 0.73 | LMNA (0.40) | — | |
| SCHEMBL8526439 | 0.69 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL8526441 | 0.69 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL28060968 | 0.69 | NOTUM (0.36) | HCRTR1HCRTR2MAP3K5USP14 | |
| SCHEMBL2401819 | 0.68 | LMNA (0.33) | — | |
| SCHEMBL1824608 | 0.68 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927458-B2 | Herbicide triazolylpyridine ketones | BAYER CROPSCIENCE AG (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8658798-B2 | Herbicide triazolylpyridine ketones | BAYER CROPSCIENCE AG (DE) | 2014-02-25 | — | — | US | disclosed |
| US-20130296168-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2013-11-07 | — | — | US | disclosed |
| US-20110237800-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| EP-2185536-B1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | BAYER CROPSCIENCE AG (DE) | 2011-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296168-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | DDT, PDK4, BCKDK | HCRTR1 313/4885HCRTR2 359/4885KDM6B 1561/4885 |
| US-20110237800-A1 | HERBICIDE TRIAZOLYLPYRIDINE KETONES | DDT, PDK4, BCKDK | HCRTR1 356/4885HCRTR2 344/4885KDM6B 1507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.