Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MLYCD | O95822 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15204487 | 0.87 | ALDH1A1 (0.68) | ALDH1A1RAB9AMAPK1MLYCDHPGD | |
| SCHEMBL24175853 | 0.87 | ALDH1A1 (0.68) | ALDH1A1RAB9AMAPK1HPGDMEN1 | |
| SCHEMBL18896210 | 0.86 | TAS1R3 (0.65) | ALDH1A1RAB9AMAPK1LMNACYP1A2 | |
| SCHEMBL8590217 | 0.85 | MLYCD (0.70) | ALDH1A1RAB9AMLYCDHPGDLMNA | |
| SCHEMBL17845261 | 0.85 | ALDH1A1 (0.66) | ALDH1A1RAB9AMAPK1HPGDLMNA | |
| SCHEMBL24175872 | 0.85 | HTT (0.72) | ALDH1A1RAB9AMAPK1HPGDLMNA | |
| SCHEMBL13767830 | 0.85 | HTT (0.72) | ALDH1A1RAB9AMAPK1HPGDLMNA | |
| SCHEMBL29833379 | 0.85 | ALDH1A1 (0.66) | ALDH1A1RAB9AMAPK1HPGDLMNA | |
| SCHEMBL24571817 | 0.85 | ALDH1A1 (0.76) | ALDH1A1RAB9AMAPK1MLYCDHPGD | |
| SCHEMBL14117645 | 0.85 | ALDH1A1 (0.66) | ALDH1A1RAB9AMAPK1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207525-A1 | Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents; bioavailability; coupling; chemical intermediates | PHARMASCIENCE INC. (CA) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207525-A1 | Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents; bioavailability; coupling; chemical intermediates | BIRC5, XIAP, BAX | ALDH1A1 3619/4885RAB9A 1476/4885MAPK1 795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.