Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526394 | 0.98 | DRD2 (0.70) | DRD2KMT2AABCG2DRD3 | |
| Hydrochloric Acid SCHEMBL8526581 | 0.97 | DRD2 (0.69) | DRD2KMT2AABCG2DRD3 | |
| Hypochlorous Acid SCHEMBL8526597 | 0.92 | KDM4E (0.67) | DRD2KMT2ADRD3 | |
| SCHEMBL8527263 | 0.90 | KDM4E (0.69) | DRD2KMT2ADRD3 | |
| Hydrochloric Acid SCHEMBL8526594 | 0.89 | KDM4E (0.68) | DRD2KMT2ADRD3 | |
| SCHEMBL8526543 | 0.87 | DRD3 (0.68) | DRD2ABCG2DRD3 | |
| SCHEMBL10355539 | 0.87 | DRD2 (0.80) | DRD2ABCG2DRD3 | |
| Hydrochloric Acid SCHEMBL9088683 | 0.86 | DRD3 (0.67) | DRD2ABCG2DRD3 | |
| SCHEMBL8526406 | 0.84 | DRD2 (0.69) | DRD2ABCG2 | |
| SCHEMBL8527005 | 0.82 | SIGMAR1 (0.68) | DRD2KMT2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539281-B1 | Naphthamides, process for their preparation and their application in the therapeutical field | INST NAT SANTE RECH MED (FR) | 1998-12-30 | — | — | EP | claimed |