Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 14/20 | 1.00 |
| ▸ | TTR | P02766 | 5/20 | 0.70 |
| ▸ | DPP4 | P27487 | 1/20 | 0.68 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | FYN | P06241 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30448943 | 1.00 | APP (1.00) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL20942195 | 1.00 | APP (1.00) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL23310889 | 0.87 | APP (0.77) | APPTTRDPP4AKR1B1CYP3A4 | |
| SCHEMBL29578214 | 0.86 | APP (0.76) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL9682411 | 0.86 | APP (0.76) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL14232132 | 0.85 | MAOB (0.74) | APPTTRAKR1B1CYP3A4ALOX15 | |
| SCHEMBL959185 | 0.85 | MAOB (0.74) | APPTTRAKR1B1CYP3A4ALOX15 | |
| SCHEMBL9044207 | 0.85 | APP (0.73) | APPTTRDPP4MAPT | |
| SCHEMBL9044203 | 0.85 | APP (0.73) | APPTTRDPP4MAPT | |
| SCHEMBL20883234 | 0.84 | APP (0.83) | APPTTRDPP4AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |
| JP-6024132-A | — | — | None | — | — | JP | disclosed |
| CN-112891334-B | Application of caffeic acid derivatives in preparation of medicine for treating gonorrhea | 浙江大学 | 2022-05-03 | — | — | CN | disclosed |
| CN-112891334-A | Application of caffeic acid derivatives in preparation of medicine for treating gonorrhea | 浙江大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-104365598-B | Caffeic acid and the application of Arrcostab in bacterial wilt control thereof | JIANGSU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-03-30 | — | — | CN | disclosed |
| CN-104823974-A | Applications of caffeic acid alkyl ester | UNIV JIANGSU SCIENCE & TECH | 2015-08-12 | — | — | CN | disclosed |
| CN-104823974-A | Applications of caffeic acid alkyl ester | UNIV JIANGSU SCIENCE & TECH | 2015-08-12 | — | — | CN | disclosed |
| CN-104365598-A | Caffeic acid and application of alkyl ester of caffeic acid in control of bacterial wilt | UNIV JIANGSU SCIENCE & TECH | 2015-02-25 | — | — | CN | disclosed |
| CN-103173502-A | Biosynthesis method of caffeic acid phenethylester by means of transesterification | UNIV JIANGSU SCIENCE & TECH | 2013-06-26 | — | — | CN | disclosed |
| US-5952263-A | PROTECTIVE LAYER FORMED OF A RESIN WITH MICROSCOPICALLY ROUGH SURFACE HORIZONTALLY CUT AT EQUALLY SPACED INTERVALS; HIGH TRANSPARENCY, IMAGE QUALITY WITHOUT WHITE STREAKS AND NONSTICKING TO THERMAL PRINTHEADS | RICOH COMPANY, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| US-5935899-A | PROTECTIVE LAYER COMPRISING SPHERICAL FILLER AND AN IRREGULAR SHAPED FILLER; NON-STICKING TO THERMAL HEAD, NO WHITE STRIPE, DECREASED HEAD DEFACEMENT; COMPUTERS, FACSIMILE MACHINES; LABEL PRINTERS | RICOH COMPANY, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5866507-A | BLEND OF BINDER AND COLORING AGENT | RICOH COMPANY, LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5792724-A | HIGH TRANSMITTANCE DENSITY, EXCELLENT REPRODUCIBILITY OF FINE DOT AND HALF TONE IMAGES; MIXTURE OF BINDER RESINS WITH DIFFERENT GLASS TRANSIFION TEMPERATURES | RICOH CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| JP-H0624132-A | REVERSIBLE THERMAL COLOR-DEVELOPING COMPOSITION AND REVERSIBLE THERMAL RECORDING MEDIUM USING SAID COMPOSITION | RICOH CO LTD | 1994-02-01 | — | — | JP | disclosed |