SCHEMBL9044203

SCHEMBL9044203

C=CCOC(=O)/C=C/c1ccc(OC)c(O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 0.73
TTR P02766 3/20 0.63
EPHX2 P34913 3/20 0.62
MAOB P27338 2/20 0.59
MAPT P10636 1/20 0.59
MAOA P21397 1/20 0.57
BACE1 P56817 3/20 0.56
TUBB1 Q9H4B7 2/20 0.54
TUBB4A P04350 1/20 0.54
TUBB P07437 1/20 0.54
TUBA3C P0DPH7 1/20 0.54
TUBA1B P68363 1/20 0.54
TUBA4A P68366 1/20 0.54
TUBB4B P68371 1/20 0.54
TUBB3 Q13509 1/20 0.54
TUBB2A Q13885 1/20 0.54
TUBB8 Q3ZCM7 1/20 0.54
TUBA3E Q6PEY2 1/20 0.54
TUBA1A Q71U36 1/20 0.54
TUBA1C Q9BQE3 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9044207 1.00 APP (0.73) APPTTREPHX2MAOBMAPT
SCHEMBL14232132 0.90 MAOB (0.74) APPTTREPHX2MAOBMAPT
SCHEMBL959185 0.90 MAOB (0.74) APPTTREPHX2MAOBMAPT
SCHEMBL23869888 0.86 APP (0.60) APPTTREPHX2MAOBMAPT
SCHEMBL28519058 0.86 FDPS (0.65) APPTTREPHX2MAOBFDPS
SCHEMBL31247977 0.85 MAOB (0.80) APPTTREPHX2MAOBMAPT
SCHEMBL4436392 0.85 MAOB (0.80) APPTTREPHX2MAOBMAPT
SCHEMBL20942195 0.85 APP (1.00) APPTTRMAPTDPP4
SCHEMBL8526723 0.85 APP (1.00) APPTTRMAPTDPP4
SCHEMBL30448943 0.85 APP (1.00) APPTTRMAPTDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705817-A1 New cannamide derivatives and their use as allergy inhibitors TSUMURA & CO. (JP) 1996-04-10 EP disclosed
US-5344845-A Methyl 4(4-acetoxy-3-methoxycinnamanide and salts as an immunosuppressive drug for allergic reactions TSUMURA & CO. (JP) 1994-09-06 US disclosed
EP-0535250-A1 NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE TSUMURA & CO. (JP) 1993-04-07 EP disclosed