Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089235 | 0.85 | AKR1C3 (0.41) | ALOX5PTGS1PTGS2LMNASMN1; SMN2 | |
| SCHEMBL8526840 | 0.81 | FOS (0.47) | ALOX5PTGS1PTGS2LMNASMN1; SMN2 | |
| SCHEMBL5245151 | 0.78 | MAOB (0.58) | ALOX5LMNASMN1; SMN2MAPTNPC1 | |
| SCHEMBL27486273 | 0.78 | MAOB (0.58) | ALOX5LMNASMN1; SMN2MAPTNPC1 | |
| SCHEMBL9076138 | 0.77 | HDAC8 (0.54) | LMNAKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL8948448 | 0.76 | MAOB (0.61) | ALOX5PTGS1PTGS2LMNASMN1; SMN2 | |
| SCHEMBL27678501 | 0.74 | ALOX5 (0.46) | ALOX5PTGS1PTGS2LMNASMN1; SMN2 | |
| SCHEMBL4239993 | 0.72 | ALOX5 (0.52) | ALOX5PTGS1PTGS2LMNASMN1; SMN2 | |
| SCHEMBL18296917 | 0.72 | ALOX5 (0.47) | ALOX5PTGS1PTGS2LMNASMN1; SMN2 | |
| SCHEMBL9026432 | 0.71 | ALOX5 (0.63) | ALOX5PTGS1PTGS2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651006-B1 | Piperidinyl phosphite compositions and polyolefin compositions containing them | MONTELL NORTH AMERICA INC (US) | 1998-03-11 | — | — | EP | claimed |
| EP-0522233-B1 | Impact resistant graft copolymers | HIMONT INC (US) | 1995-06-07 | — | — | EP | claimed |
| EP-0286522-B1 | HIGHLY PURE ALDITOL DIACETALS FREE FROM TRACES OF ORGANIC SOLVENTS, AND PROCESSES FOR THEIR PREPARATION | Roquette FrÀ¨res (FR) | 1992-11-11 | — | — | EP | claimed |