SCHEMBL8526958

SCHEMBL8526958

CC(C)(C)c1ccc2sc(=S)sc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35
RECQL P46063 1/20 0.35
KMT2A Q03164 1/20 0.35
TSHR P16473 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
PLA2G1B P04054 1/20 0.33
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SENP8 Q96LD8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10064217 0.79 ALDH1A1 (0.41) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL2706410 0.71 ALDH1A1 (0.43) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL12473850 0.71 KIF11 (0.47) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL24604645 0.69 KIF11 (0.42) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL10408804 0.68 KDM4E (0.31) ALDH1A1HPGDALOX15TDP1KDM4E
SCHEMBL10132023 0.67 ALDH1A1 (0.39) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL1754103 0.65 DHPS (0.39) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL12873186 0.65 DHPS (0.39) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL8279312 0.65 TSHR (0.38) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL24051076 0.64 TSHR (0.46) ALDH1A1HPGDALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0410654-B1 Light- sensitive composition FUJI PHOTO FILM CO LTD (JP) 1998-10-28 EP disclosed
US-5064747-A Improved photosensitivity using an unsaturated 1,3-dithiol-2-ylidene derivative; lithographic printing plates; photoresists FUJI PHOTO FILM CO., LTD. (JP) 1991-11-12 US disclosed
US-5061605-A IMPROVED SENSITIVITY TO LONG WAVELENGTHS FUJI PHOTO FILM CO., LTD. (JP) 1991-10-29 US disclosed