Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 6/20 | 0.48 |
| ▸ | PPIB | P23284 | 2/20 | 0.45 |
| ▸ | PPIG | Q13427 | 2/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 10/20 | 0.44 |
| ▸ | F2 | P00734 | 7/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8641408 | 0.99 | PPID (0.48) | PPIDPPIBPPIGPPIAF10 | |
| SCHEMBL8526765 | 0.85 | F10 (0.45) | F10F2PRSS1TMPRSS6 | |
| SCHEMBL1389096 | 0.84 | F10 (0.43) | F10F2PRSS1 | |
| SCHEMBL7123147 | 0.82 | PPID (0.48) | PPIDPPIBPPIGPPIAF2 | |
| SCHEMBL6895115 | 0.82 | PPID (0.48) | PPIDPPIBPPIGPPIAF2 | |
| SCHEMBL1389004 | 0.80 | F10 (0.44) | F10F2PRSS1 | |
| SCHEMBL7058207 | 0.80 | PRSS1 (0.41) | F10F2PRSS1 | |
| SCHEMBL6900983 | 0.80 | PRSS1 (0.41) | F10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL8121834 | 0.80 | F10 (0.43) | F10F2PRSS1 | |
| SCHEMBL8525704 | 0.80 | F10 (0.44) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |