Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893927 | 0.70 | HTT (0.38) | P2RX7HTTNPSR1CYP19A1PDK1 | |
| SCHEMBL8619928 | 0.70 | ABCC9 (0.37) | P2RX7HTTNPSR1CYP19A1PDK1 | |
| SCHEMBL7887002 | 0.70 | HTT (0.41) | P2RX7HTTNPSR1CYP19A1PDK1 | |
| SCHEMBL7896906 | 0.70 | HTT (0.39) | P2RX7HTTNPSR1CYP19A1PDK1 | |
| SCHEMBL8621788 | 0.69 | ABCC9 (0.38) | P2RX7HTTNPSR1CYP19A1PDK1 | |
| SCHEMBL14107962 | 0.69 | CYP2A6 (0.47) | P2RX7HTTNPSR1PDK1PDK2 | |
| SCHEMBL7887079 | 0.68 | HTT (0.36) | P2RX7HTTNPSR1CYP19A1PDK1 | |
| SCHEMBL13874238 | 0.68 | NR3C1 (0.46) | P2RX7HTTNPSR1PDK1PDK2 | |
| SCHEMBL5110282 | 0.67 | HTT (0.50) | P2RX7HTTNPSR1CYP19A1PDK1 | |
| SCHEMBL5912934 | 0.67 | HTT (0.45) | P2RX7HTTNPSR1CYP19A1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927034-A1 | METHOD OF TREATING URINARY INCONTINENCE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-07-07 | — | — | EP | claimed |
| WO-1998011888-A1 | METHOD OF TREATING URINARY INCONTINENCE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-26 | — | — | WO | claimed |