Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009509 | 0.82 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2TDP1HTTALDH1A1 | |
| SCHEMBL8526830 | 0.76 | RECQL (0.42) | RECQLLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL2962266 | 0.75 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2TDP1HTTALDH1A1 | |
| SCHEMBL1360933 | 0.74 | HSD17B10 (0.55) | LMNASMN1; SMN2HTTALDH1A1NPSR1 | |
| SCHEMBL16950729 | 0.74 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2TDP1HTTALDH1A1 | |
| SCHEMBL13332291 | 0.74 | TDP1 (0.44) | LMNASMN1; SMN2TDP1HTTALDH1A1 | |
| SCHEMBL9447508 | 0.73 | PDE7A (0.50) | LMNASMN1; SMN2HTTALDH1A1NPSR1 | |
| SCHEMBL10498142 | 0.73 | ALDH1A1 (0.50) | LMNASMN1; SMN2TDP1HTTALDH1A1 | |
| SCHEMBL8528296 | 0.72 | RECQL (0.40) | RECQLLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL9447492 | 0.72 | HSPB1 (0.48) | LMNASMN1; SMN2TDP1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596358-B1 | 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles | BAYER AG (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5484953-A | CHEMICAL INTERMEDIATES FOR BENZIMIDAZOLES FOR INSECTICIDES OR NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-16 | — | — | US | disclosed |
| EP-0596358-A1 | 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles | BAYER AG (DE) | 1994-05-11 | — | — | EP | disclosed |