SCHEMBL9114540

SCHEMBL9114540

O=C(O)C(C(Cn1ccnc1)C(C(=O)O)P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FDPS P14324 4/20 0.61
GGPS1 O95749 3/20 0.46
BTN3A1 O00481 1/20 0.46
CA12 O43570 1/20 0.46
CA2 P00918 1/20 0.46
LMNA P02545 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP14 P50281 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
ALDH1A1 P00352 1/20 0.46
EGLN3 Q9H6Z9 1/20 0.44
TBXAS1 P24557 9/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8843686 0.86 FDPS (0.59) FDPSGGPS1BTN3A1CA12CA2
SCHEMBL8843300 0.79 FDPS (0.51) FDPSGGPS1BTN3A1CA12CA2
SCHEMBL8843708 0.78 TBXAS1 (0.50) FDPSGGPS1BTN3A1CA12CA2
SCHEMBL515542 0.76 FDPS (1.00) FDPSGGPS1BTN3A1CA12CA2
SCHEMBL6790628 0.76 ALDH1A1 (0.59) FDPSALDH1A1EGLN3TBXAS1
Water SCHEMBL28274320 0.75 FDPS (0.96) FDPSGGPS1BTN3A1CA12CA2
SCHEMBL3659339 0.75 FDPS (0.71) FDPSGGPS1BTN3A1CA12CA2
SCHEMBL8843691 0.75 TBXAS1 (0.60) FDPSTBXAS1
Hydrochloric Acid SCHEMBL5316934 0.74 TBXAS1 (0.60) FDPSALDH1A1EGLN3TBXAS1
SCHEMBL8843380 0.74 TBXAS1 (0.63) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995011249-A1 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING THEM AND DRUGS CONTAINING THEM BOEHRINGER MANNHEIM GMBH (DE) 1995-04-27 WO disclosed