SCHEMBL8527767

SCHEMBL8527767

C/C=C\NC(=O)c1sc(Cl)cc1[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7223067 0.74 DAO (0.34) KDM4EMAPTHPGDL3MBTL1KMT2A
SCHEMBL7217318 0.74 ALDH1A1 (0.44) KDM4EHPGD
SCHEMBL7225331 0.73 GSK3B (0.35) KDM4EMAPTHPGDKMT2A
Hydrochloric Acid SCHEMBL7223071 0.73 ALDH1A1 (0.43) KDM4EHPGD
SCHEMBL27431253 0.72 ALDH1A1 (0.33) KDM4EMAPTHPGDL3MBTL1KMT2A
SCHEMBL7224229 0.70
SCHEMBL7219539 0.69 RAB9A (0.40) KDM4EMAPTHPGDL3MBTL1
SCHEMBL7217843 0.69 RAB9A (0.40) KDM4EMAPTHPGDL3MBTL1
SCHEMBL7217850 0.69 RAB9A (0.40) KDM4EMAPTHPGDL3MBTL1
SCHEMBL7224809 0.66 ALOX5 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811411-A Fungicides for the control of take-all disease of plants MONSANTO COMPANY (US) 1998-09-22 US claimed