Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.63 |
| ▸ | MEN1 | O00255 | 8/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7244275 | 0.89 | GAA (0.69) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL10160140 | 0.82 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL7246958 | 0.82 | KMT2A (0.72) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL1028389 | 0.82 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL1028387 | 0.82 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL7245406 | 0.82 | NLRP3 (0.58) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL7235999 | 0.82 | KMT2A (0.60) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL6754266 | 0.81 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL7238120 | 0.81 | USP2 (0.67) | ALDH1A1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL9258004 | 0.81 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0887341-A1 | Amide derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-12-30 | — | — | EP | disclosed |