Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531354 | 0.84 | HTR1A (0.41) | MIFMTNR1AMTNR1BADRA1AHTT | |
| SCHEMBL8901795 | 0.80 | MIF (0.43) | MIFMTNR1AMTNR1BADRA1AHTT | |
| SCHEMBL8903352 | 0.79 | MIF (0.42) | MIFMTNR1AMTNR1BADRA1AHTT | |
| SCHEMBL8901652 | 0.78 | CYP1A2 (0.39) | MTNR1AMTNR1BADRA1A | |
| SCHEMBL8527142 | 0.70 | MIF (0.46) | MIFMTNR1AMTNR1BADRA1AHTT | |
| SCHEMBL8900793 | 0.68 | AKT1 (0.34) | MIF | |
| SCHEMBL8528137 | 0.68 | MIF (0.42) | MIFMTNR1AMTNR1BADRA1A | |
| SCHEMBL8903292 | 0.68 | ADRA1A (0.41) | MIFMTNR1AMTNR1BADRA1AHTT | |
| SCHEMBL8899620 | 0.68 | AKT1 (0.50) | — | |
| SCHEMBL9755768 | 0.67 | ADRA1A (0.40) | MIFMTNR1AMTNR1BADRA1AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | claimed |
| US-5736523-A | ADMINISTERING TO THE MAMMAL SUFFERING FROM CANCER | BIOCHEM PHARMA INC. (CA) | 1998-04-07 | — | — | US | disclosed |
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | disclosed |
| WO-1995012588-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC. (CA) | 1995-05-11 | — | — | WO | disclosed |